The best UK cancer charities

Behind every breakthrough in the lab and every hand held through treatment is someone who cares: the scientists, nurses, youth workers and fundraisers who stand with people facing cancer. It's hopeful, determined work, and it means no one has to face cancer alone.

Can't choose? Donate to them all at once

Runners in bright kit taking part in the London Marathon past the towers of Canary Wharf
Two people holding hands in a quiet moment of support
Two friends talking on a wall by the Thames, with St Paul's Cathedral behind them
A scientist in a lab coat using a pipette to transfer liquid into small tubes at a research bench
Two people wrapped up warm on a grassy hillside, looking out over Edinburgh

Four charities, each brilliant at a different part of the job.

Rather than a ranked list, we've picked a range of charities, so together they cover more than any one could alone.

  • Cancer Research UK logo

    Cancer Research UK

    • Cancer Research
    • Clinical Trials
    • Nurse Helpline

    Cancer Research UK was formed in 2002, but its history goes back to 1902 and the founding of the Imperial Cancer Research Fund. Today it's the world's largest charitable funder of cancer research, working to beat more than 200 types of cancer. Its LungVax team is preparing to trial the world's first preventative lung cancer vaccine. Through Cancer Chat and its nurse helpline, it's there for people living with cancer right now too, so hope for tomorrow comes with help today.

    Key stats

    Scientists, doctors and nurses supported
    6,000+
    Clinical trials supported
    100+
    People who took part in Race for Life
    240,000+
    Interactions with Cancer Chat, its nurses and information
    27m

    Source: Cancer Research UK Annual Report 2025/26

    Why we've included them

    Cancer Research UK takes on cancer in all its forms, working to beat more than 200 types. Its clinical trials and a preventative lung cancer vaccine aim to change the outlook for whichever cancer a family faces.

  • Macmillan Cancer Support logo

    Macmillan Cancer Support

    • Cancer Nurses
    • Support Line
    • Financial Help

    In 1911, Douglas Macmillan watched his father die of cancer and set up a society to make the experience of cancer better. Today Macmillan's nurses and professionals support people living with cancer across the UK. Its Support Line is there 365 days a year, with help on everything from treatment to money worries, and its Online Community never closes. Its volunteer Buddies offer a friendly ear when it's needed most, and that small human touch goes a long way.

    Key stats

    People living with cancer supported
    476,000
    Macmillan nurses and professionals
    11,000+
    Potential benefits identified for people
    £112m
    Volunteers giving their time
    31,000+

    Source: Macmillan Cancer Support Annual Report 2025

    Why we've included them

    Macmillan is there for everyday life with cancer, with nurses and a Support Line open 365 days a year. Its help with money worries and its volunteer Buddies make life with cancer a little easier, day to day.

  • Teenage Cancer Trust logo

    Teenage Cancer Trust

    • Teenage Cancer Units
    • Specialist Nurses
    • Youth Workers

    Teenage Cancer Trust was founded in 1990 by Myrna and Adrian Whiteson, and opened the first cancer ward designed for teenagers and young adults at London's Middlesex Hospital. It's there for anyone aged 13 to 24 diagnosed with cancer, from diagnosis to two years after treatment. Its specialist nurses and youth workers care for young people on its units, in local hospitals and at home. Its Royal Albert Hall gigs bring stars together for them, and we love that bit of rock and roll.

    Key stats

    Specialist units in NHS hospitals
    28
    Specialist nurses and youth workers funded
    116
    One-to-one support sessions
    19,201
    Activities, from gaming nights to pizza
    ~1,000

    Source: Teenage Cancer Trust Annual Report 2025

    Why we've included them

    Teenage Cancer Trust runs specialist units in NHS hospitals for anyone aged 13 to 24 with cancer. Its nurses and youth workers care for them as young people, on the ward and at home.

  • Young Lives vs Cancer logo

    Young Lives vs Cancer

    • Social Workers
    • Homes from Home
    • Grants

    Young Lives vs Cancer, formerly CLIC Sargent, began in 1968 with a fund that helped families with costs like a father's train fare to visit his son in hospital. Today its specialist social workers stand by children and young people with cancer, from birth to 25, and their families. Its Homes from Home keep families together near hospital. Its campaigning helped win a £10 million travel fund in England, a lovely full circle for a charity born of a train fare.

    Key stats

    Children and young people supported by its social workers
    6,989
    Free nights in its Homes from Home
    20,631
    Grants for travel, food and bills
    4,889
    Welfare and housing enquiries answered
    2,212

    Source: Young Lives vs Cancer Annual Report 2024/25

    Why we've included them

    Young Lives vs Cancer brings the whole family into the picture, supporting children and young people with cancer from birth to 25. Its social workers, grants and free Homes from Home keep families together and afloat through treatment.

Cancer Research UK logoMacmillan Cancer Support logoTeenage Cancer Trust logoYoung Lives vs Cancer logo

Four amazing cancer charities. Why choose just one?

Support all four with a one-off or monthly donation, split however you like. With Legacy, giving is simple and you're always in control.

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